Developmental changes in Epac gene expression in mice
نویسندگان
چکیده
منابع مشابه
Neonatal Maternal Deprivation Response and Developmental Changes in Gene Expression Revealed by Hypothalamic Gene Expression Profiling in Mice
Neonatal feeding problems are observed in several genetic diseases including Prader-Willi syndrome (PWS). Later in life, individuals with PWS develop hyperphagia and obesity due to lack of appetite control. We hypothesized that failure to thrive in infancy and later-onset hyperphagia are related and could be due to a defect in the hypothalamus. In this study, we performed gene expression microa...
متن کاملConnexin 43 gene expression in mice with cardiopulmonary developmental defects.
Gap junctions are vital for cellular integrity, including homeostasis, morphogenesis, differentiation and growth in normal development of organs such as heart. Connexin 43 (Cx43) is a major gap junction protein. Our cDNA microarray analysis of normal and nitrofen-exposed neonatal mice with hypoplastic lungs, associated congenital diaphragmatic hernia (CDH) and heart developmental defects showed...
متن کاملChanges in Gene Expression Associated with FTO Overexpression in Mice
Single nucleotide polymorphisms in the first intron of the fat-mass-and-obesity-related gene FTO are associated with increased body weight and adiposity. Increased expression of FTO is likely underlying this obesity phenotype, as mice with two additional copies of Fto (FTO-4 mice) exhibit increased adiposity and are hyperphagic. FTO is a demethylase of single stranded DNA and RNA, and one of it...
متن کاملChanges in liver gene expression of Azin1 knock-out mice.
The ornithine decarboxylase antizyme inhibitor (AZI) was discovered as a protein that binds to the regulatory protein antizyme and inhibits the ability of antizyme to interact with the enzyme ornithine decarboxylase (ODC). Several studies showed that the AZI protein is important for cell growth in vitro. However, the function of this gene in vivo remained unclear. In our study, we analyzed the ...
متن کاملInvestigation of Changes in TC1 Gene Expression Influenced by Hydro alcoholic Extract of Fennel in Thyroid Cancer Induced in Mice: An Experimental Study
Background and Objectives: Thyroid cancer is the most common malignant endocrine, accounting for 1% of all cancers. One of the most effective genes in thyroid cancer is the TC1 gene. Therefore, this study aimed to determine TC1 gene expression changes under the influence of hydro alcoholic extract of fennel in mice. Materials and Methods: In this experimental study, hydro alcoholic extract of ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2007
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.21.6.a1152-a